This is an unedited video of me, Tasselfoot, getting well under 300 seconds on Two Rooms. It is unedited so you can see how I quickly restart, quickly change rooms, and what is and is not acceptable without restarting. You will need to restart many times on each level to get it down pat for a solid time.
My overall fastest times are down to 256.0.
Game: http://www.kongregate.com/games/sebby_man/two-rooms/?referrer=Tasselfoot
Music: Quickdraw by KgZ. http://www.rithum.com/kgzmusic