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The most common source of heavy metal toxicity is from dental amalgam fillings and other metal dental appliances. In 1989, the Environmental Protection Agency (EPA) declared that amalgams are a hazardous substance under the Superfund law. Scrap dental amalgam was declared a hazardous waste in 1988 by the EPA. Outside of your mouth it has to be: 1. Stored in unbreakable, tightly sealed containers away from heat. 2. It is not to be touched. 3. Stored under liquid glycerine or photographic fixer solution. So, once it is taken out of the mouth it is toxic, but when it is placed in the teeth it is labeled "nontoxic." You can't throw it in the trash, bury it in the ground or put it in a landfill, but they say it's okay to put it in people's mouths. It sounds like truth decay! Lead, mercury and cadmium exert most of their toxicity by destroying important proteins, many of which are enzymes, hormones, or cell receptors. Mercury will attach to sulfur amino acid building blocks in proteins. The sulfur amino acids are methionine, cysteine, and taurine. Sulfur is present in all proteins. Numerous enzymes require intact sulfur groups and many are inactivated by mercury.
Lead binds with the sulfur groups on proteins and inactivates them. Lead suppresses neuron clusters in the brain, hindering brain development in children by stunting the mapping of sensory nerves. One of the primary ways the body gets rid of metal compounds is through a pathway that goes from the liver into the bile where it is then transported to the small intestine and excreted in the feces. Inorganic mercury is complexed with glutathione in the bile, suggesting that glutathione status is a major consideration in the biliary secretion of mercury. This same pathway is affected by a mercury induced reduction of available taurine needed to produce bile acid (taurocholic acid). When the microflora of the intestine has been reduced through stress, poor diet, use of antibiotics and other drugs, fecal content of mercury is greatly reduced. Instead of being excreted in the feces, the mercury gets recirculated back to the liver. The person that is under stress, eating a poor diet, and/or taking antibiotics will tend to maintain a higher body burden of mercury derived from dietary sources--especially if they are eating diets high in fish.
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