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Sildenafil Citrate is active ingredient of this product.
Kamagra Oral Jelly is a brand name for Ajanta's Sildenafil Citrate Oral Jelly. The product is in the jelly form, meant to be consumed orally and should be allowed to dissolve in the oral cavity before it is swallowed.More easily swallowed than tablets and therefore suitable for elderly people and also people who have difficulty in swallowing.
The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP) producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum but enhances the effect of NO (Nitric oxide) by inhibiting phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by Sildenafil causes increased levels of cGMP in the corpus cavernosum resulting in smooth muscle relaxation and inflow of blood to the corpus cavemosum.
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