Zoloft - Brief History of the SSRI Antidepressant

2012-01-04 292

http://www.zoloftsertralinebirthdefects.com/ssri-antidepressants/

A big company might cut corners and if it does, you might get hurt. The antidepressant sertraline hydrochloride—sold under the brand name Zoloft—might have caused you and your baby to suffer life-threatening side effects. If a dangerous product has harmed you or a loved one, the Rottenstein Law Group can help.

Zoloft is a potent selective serotonin reuptake inhibitor manufactured and sold by American pharmaceutical giant Pfizer, Inc. Available by prescription only, the medication is used to treat major depression, obsessive-compulsive disorder, panic disorder, and anxiety disorders. First brought to market in 1991, Zoloft has since become a blockbuster antidepressant. Doctors wrote more than 29 million prescriptions for the drug in 2007, more than any other antidepressant that year.

SSRIs work by preventing certain receptors in the human brain from absorbing serotonin that has already been released. Serotonin helps maintain feelings of well-being, so preventing its re-absorption alleviates negative feelings. Unlike other drugs (such as Wellbutrin—for example), SSRIs minimally affect noradrenaline and dopamine, which regulate stress levels. But SSRIs can cause many side effects, most common among them nausea, somnolence, and sexual dysfunction.