as·sas·si·nate ( -s s -n t ). tr.v. as·sas·si·nat·ed, as·sas·si·nat·ing, as·sas· si·nates. 1. To murder (a prominent person) by surprise attack, ...0:00 Dub Assassinator, 4:08 Jahovia in Dub Majesty, 8:04 Rasta Pon Top