Manchester City fears Rodri could miss the remainder of the season with a serious knee injury in a major blow to their Premier League title defense.
Pep Guardiola's metronome was forced off 21 minutes into Sunday's tempestuous 2-2 draw with Arsenal at the Etihad Stadium.
Rodri fell into a heap clutching his right knee after falling during a run alongside Thomas Partey to meet a corner and was helped off the pitch by medical staff.
Tests undertaken on Monday uncovered the severity of the injury and a further round of examinations are expected to confirm that Rodri is set for months on the sidelines.
The Spain international will visit Dr Ramon Cugat in Barcelona for treatment and his absence will be acutely felt by Guardiola, who has built his foundations around the central midfielder.