During his school days, Yeo Jeong-Woo (Park Hyung-Sik) always placed first in academics and he studied at the top medical school in the country. Yeo Jeong-Woo is now a popular plastic surgeon. His life goes smoothly, but, due to a mysterious medical accident, his life is pushed to the edge. At this time, he meets Nam Ha-Neul (Park Shin-Hye). She was a rival in his past and he meets her at the lowest point in his life.
Nam Ha-Neul works as an anesthesiologist. When she was growing up, people called her a genius due to her extreme intelligence. She studied hard and became a doctor. Her life consists of only work and studying. She doesn't have any time to experience fun. One day, Nam Ha-Neul realizes she isn’t happy with her life and she wants to make a change. At this time, she meets Yeo Jeong-Woo during one of the worst moments in her life. They comfort each other and a romantic relationship blossoms between them.
