Operations at Ronald Reagan Washington National Airport will be suspended between roughly 6 and 10 pm.
Officials say it is not connected to Trump's "Salute to America" but many critics are not convinced.
The fireworks have been moved to a park to accommodate Trump's Lincoln Memorial display.
The last such runway closure was in 2015 for a commemorative flight of World War II-era planes.
The airport's website does not yet list arrivals and departures for Thursday, reports CNN.