A brother and sister in India suffer from a rare condition that leaves them looking many years older - just like Brad Pitts Benjamin Button film.\r
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Keshav Kumar, 18 months, and his sister Anjali Kumari, seven, have wrinkled skin, suffer pain in their joints and swollen faces.\r
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The siblings are teased for their looks and are often stared at on the streets. They dream of looking like other children their own age - but doctors say their condition has no cure. \r
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Little Anjali said: ‘I know Im different from others my age. I have a different kind of face, a different body, different everything. \r
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I have a swollen face while the rest of the world looks normal. People always stare at me and pass bad comments. \r
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The children in school call me names like daadi Amma (grandmother), budhiya (old lady), bandariya (monkey), or hanuman (a Hindu monkey lord) and it annoys me. I want to be treated like a normal kid and I want to be accepted for who I am.\r
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I really wish I could look as pretty as my sister. My parents hope that I will be okay one day but it makes me feel sad that my family suffer and feel embarrassed because of me. My only wish is for a cure. I want to live a long pain free life.\r
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The siblings suffer from a rare form of Progeria as well as a disease called Cutis Laxa, which doctors in India say is incurable. \r
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The siblings live with their father, Shatrughan Rajak, 40, mother Rinki Devi, 35, in Ranchi, Jharkhand, and their older sister daughter Shilpi, 11, who do not have the disease. \r
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Father Shatrughan, a laundry man earning 4,500 Rupees a month (£45), said: ‘We dream there is a cure for my children. \r
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People in our community call them ‘old and its heartbreaking. Weve tried to get help from our local doctors but they have told us our only hope is from overseas.\r
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After Rinki gave birth to her first daughter Shilpi, they were quick to build their family, but when Anjali, their second, was just six months old she was rushed to hospital with pneumonia.\r
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‘After she recovered from, the moisture in her body just seemed to dry up and her skin loosened, added Shatrughan. \r
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‘We took her back to our doctor at a government hospital but they said theres no cure for her and her life was in the lords hand.\r
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But five years later Shatrughan and Rinki decided to have another child, a boy Keshav was born, and in time they noticed he too suffered the same condition as his sister.\r
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‘We havent taken Keshav to any doctor because we know he has the same as his sister, Shatrughan said. \r
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‘Were a poor family and doctor visits are expensive. They couldnt do anything for Anjali so we knew they couldnt do anything for Keshav either.\r
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Their sister Shilpi, 11, is very protective of her siblings - and said: ‘I hate it when people tease them. \r
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I get very upset but theres nothing I can say, what do I say back to these cruel kids? I will be here for them forever but I just wish them the best education so that they are never dependent on anyone for anything as they grow up. I will teach them to be strong. \r
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Anjali already experiences ailments usually suffered by pensioners. Her joints hurt, she has breathing issues, her skin is sagging and her eye sight is poor. And due to her low immunity she picks up illnesses quickly.\r
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While Anjali goes to school and is very aware of her unusual condition, Keshav is too young to notice.\r
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Mother Rinki, 35, said: ‘I massage Anjalis legs all the time, shes always in pain. It breaks my heart to see my kids this way. Anjali keeps asking when will she be like her sister. Shes very much aware and is affected by her appearance. \r
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‘I can just about afford homeopathic medicines which I hope eases their ailments but I just cant afford allopathic medicines, he added. \r
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Dr Kailash Prasad, a child specialist at a government hospital in Ranchi examined the siblings and said: ‘This looks like a genetic disease and most likely to be Progeria. \r
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The other possibility is Cutis Laxa. The complications in the two are more or less the same. It is an extremely rare disorder.\r
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‘Theyre stable as of now but theyre very prone to issues due to their low immunity. The old age symptoms have already started and the risk of heart attack, chest infections, arthritis and so on is growing in them which usually comes in old age for a normal person. \r
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Professor Ted Brown, Geneticist Director at NYS Institute for Basic Research in Developmental Disabilities, in New York, is an expert in developmental disabilities and often assists the Progeria Research Foundation.\r
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He said: I would suggest (these siblings) may have a form of Cutis Laxa which has some resemblance to Progeria or prema
