The prostate often enlarges as men get older, but now a day due to modern lifestyle major part of the male population is suffering from prostate problems. These prostate problems not only disturb the functional life of a person but also disturb the personal life. Anatomically prostate gland is compromised of zones and lobes. The main action of the prostate gland is in the sexual sphere, where it produces PSA which is an essential protein which helps to keep the semen in its liquid state. This PSA when gets increased can lead to cancer or any prostate problem. Major risk factors associated with prostate problems are related to old age (above 45), more in person with a family history of cancer. Diet factors also play a major role as long-term medication, smoking, alcohol, night working and even increased intake of tea and coffee leads to prostate problems. The prostate often enlarges as men get older, but now a day due to modern lifestyle major part of the male population is suffering from prostate problems. These prostate problems not only disturb the functional life of a person but also disturb the personal life. Anatomically prostate gland is compromised of zones and lobes. The main action of the prostate gland is in the sexual sphere, where it produces PSA which is an essential protein which helps to keep the semen in its liquid state. This PSA when gets increased can lead to cancer or any prostate problem. Major risk factors associated with prostate problems are related to old age (above 45), more in person with a family history of cancer. Diet factors also play a major role as long-term medication, smoking, alcohol, night working and even increased intake of tea and coffee leads to prostate problems. The epithelial cells in the prostate gland produce a protein called PSA (prostate-specific antigen). The PSA helps keep the semen in its liquid state. Some of the PSA escapes into the bloodstream. We can measure a man's PSA levels by checking his blood. If a man's levels of PSA are high, it might be an indication of either prostate cancer or some kind of prostate condition. Male hormones affect the growth of the prostate, and also how much PSA the prostate produces. If male hormones are low during a male's growth and during his adulthood, his prostate gland will not grow to full size. Mostly in older men, the prostate may continue to grow, especially the part that is around the urethra. This can make it more difficult for the man to pass urine as the growing prostate gland may be causing the urethra to collapse. When the prostate gland becomes too big in this way, the condition is called Benign Prostatic Hyperplasia (BPH). “Only 30 percent of patients with high PSA are detected cancer after biopsy it shows PSA test is not distinctive indicator of cancer of prostate but may also detect prostatitis and Benign hypertrophy of prostate “The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA Screening as most of the canc