The S&P 500 index showed five new 52-week highs and three new lows, while the Nasdaq recorded 11 new highs and 16 new lows.
The S&P 500 healthcare index plunged 0.91 percent, setting it up for its worst day since Jan.
11, when Trump said drugmakers were "getting away with murder" by charging high prices.
ET (1435 GMT), the Dow was down 28.62 points, or 0.14 percent, at 20,925.72, the S&P 500 was down 4.79 points, or 0.20 percent, at 2,370.52
and the Nasdaq Composite was down 7.35 points, or 0.13 percent, at 5,841.82.
Newly minted shares of Snapchat owner Snap Inc fell 8.5 percent to $21.70 after a group representing large institutional investors asked stock index providers to bar the company
and others who sell non-voting shares from their stock benchmarks.
Johnson & Johnson was the top drag on the S&P 500 and the Dow Jones Industrial Average, while Amgen had a similar influence on the Nasdaq.
The Federal Reserve has left no stone unturned in preparing the markets for tighter monetary policy, with an unusual number
of key officials including Fed Chair Janet Yellen hinting at a rate hike in the central bank’s March 14-15 meeting.
(Reuters) - Healthcare stocks took a hammering on Tuesday, dragging the major U. S.
indexes lower, after President Donald Trump tweeted about lowering drug prices.
Nine of the other 11 major S&P sectors marked slight losses as investors position themselves for an interest rate hike next week.
The healthcare selloff could lead to the first back-to-back losses for the S&P 500 and the Dow in more than one month.