Jamshed first gained nationwide prominence and international recognition as group 'Vital Signs' vocalist in 1987 with the album, Vital Signs 1. It included the singles "Dil Dil Pakistan", and "Tum Mil Gaye". The commercial success of Vital Signs' first album helped develop Pakistan's rock music industry
Junaid Jamshed and his second wife died on 7 December 2016 when PIA Flight 661 crashed in Havelian. The flight was enroute to Islamabad from Chitral. He was in Chitral for a Tablighi Jamaat mission and was returning to Islamabad