Contribution of the Arterial System and the Heart to Blood Pressure during Normal Aging - A Stimulation Study
By:
By Maksuti E, Westerhof N, Westerhof B, Broomé M, Stergiopulos N [CC BY 4.0]
[Study] Article: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920393/
Study’s Conclusion: This study shows that both the arterial system and the heart contribute to the blood pressure changes in normal aging and quantifies the arterial and cardiac contributions to blood pressure over a wide age range (20 to 80 years).
The changes in arterial properties initiate a systolic pressure increase, which in turn initiates a cardiac remodeling process that further augments the systolic pressure and mitigates the decrease in diastolic pressure.
The close agreement between simulated pressure changes and published data supports the idea that the approach presented may be applicable to the analysis of arterial and cardiac changes in both health and disease. More data on arterial and cardiac function in aging would help future refinement of the model and application to other conditions.
