This video describes how to configure S2 type XBEE modules using XCTU software & USB breakout boards.
S2 modules are configured as COORDINATOR/ROUTER nodes by feeding in the 64 bit Module address of opposite XBEE as Destination address.
http://alselectro.wordpress.com/2013/01/13/xbee-radios-configuring-series-2-with-xctu/
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