The San Francisco 49ers will travel in NFC West play as they take on the St Louis Rams in an NFL Pro Football game scheduled for Thursday night.
Kick off time from St Louis is scheduled for 8:25PM Eastern Time with national television coverage provided by the NFL Network.
The Thursday Night Football odds from this week four game have the road team San Francisco 49ers favored by -3 points with an over under line set at 42 ½ points.