The Indianapolis Colts will hit the road for a week three NFL pro football game against the San Francisco 49ers on Sunday afternoon.
Start time from San Francisco is set for 4:25PM Eastern Time with national television coverage provided by CBS.
The NFL odds from this contest have the home team San Francisco 49ers favored by -10 points with an over under line set at 46 points. A money line play on San Francisco will return -450 odds with bettors playing Indianapolis on the money line receiving +325 odds return.
